Using organoids to evaluate the effect of toxins on S. suis translocation

23-05-2025 | |
Using organoids to evaluate the effect of toxins on S. suis translocation
The use of porcine ileal organoids offers possibilities for testing the effect of dietary interventions without conducting in vivo studies. Photo: Mark Pasveer
Fusarium mycotoxins such as deoxynivalenol (DON) frequently contaminate pig diets, often co-occurring with others like T-2 toxin. These toxins weaken intestinal barrier, raising infection risks. This study explores their effects on Streptococcus suis translocation using organoid models. Fusarium mycotoxins such as deoxynivalenol (DON) commonly contaminate most pig diets (88%), often co-contaminating with other mycotoxins. For example, DON and T-2 toxin co-contamination is expected in 45% of g


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Redacteur 1

Vincent
ter Beek

Redacteur 2

Kees van
Dooren

Redacteur 3

Treena
Hein

Santos
Regiane Santos Mycotoxins researcher, Schothorst Feed Research
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