Seneca Valley virus: What is known?

The emergence of Seneca Valley virus (SVV) and increased incidences of SVV-associated vesicular disease alarmed the US swine industry. On the plus side, this gave the opportunity to gain a better understanding of the pathogenesis, ecology and immunobiology of this lesser-known disease. Seneca Valley virus (SVV) is a small non-enveloped virus with a positive-sense, single-stranded RNA genome of approximately 7.2 kilobases. As is the case for all RNA viruses, a relatively high rate of genetic mut