Pleuromutilin susceptibility of Clostridium perfringens and Clostridium difficile isolates from pigs in Italy and Denmark

Clostridium perfringens type A is a causative agent of diarrhea in neonatal piglets with widespread occurrence in many pig producing areas; indeed the consensus ß2 toxin (cpb2con) was recently considered the key virulence factor characterising the strains involved in neonatal enteritis of pigs (1, 2). The role of Clostridium difficile in neonatal diarrhea is increasing and becoming of greater clinical importance (3, 4) in many countries. Aim of the study was to assess the MIC values of toxigen