Reducing antimicrobial use and ZnO consumption on farms

Replacing antibiotics and ZnO requires a comprehensive approach. Studies show that early vaccination against Oedema disease is a successful tool for reducing mass medication with colistin and ZnO on farms. Oedema disease (OD) is one of the major diseases in pigs during nursery causing significant losses on affected farms. It is caused by strains of E. coli producing Shiga toxin (STEC), specifically Shiga toxin 2 subtype e (Stx2e). These strains are mostly equipped with fimbrial adhesins F18ab